Please, please PLEASE don't give up on making more Muppet movies. I'm sure your people are trying to figure out what went wrong. Well, I can tell you EXACTLY what went wrong: you released the movie at the wrong time. If you'd given it a holiday release, it would have done boffo box office; I can practically guarantee it. So please don't give up on them, and for God's sake DON'T screw around with the formula or dumb down the comedy. Just release it at the right time and it will work. Trust me. In fact, you should re-release it this year during the holiday season, and then you'll see for yourselves that I'm right.
To everyone within the sound of my typing: please, please, PLEASE purchase a copy (or several copies would be even better) of Muppets Most Wanted in the format of your choice. Think of it as paying ransom; if Disney doesn't get enough money, they will keep the Muppets locked up indefinitely in drawers and boxes.